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Research indicates that chemogenetic stimulation of hiPSC-derived neural cells enhances cell activity and neuron-to-neuron interactions in vitro

10.1186/s40798-015-0009-9

[2] [8] In such cases, your doctor might consider additional testssuch as serum methylmalonic acid (MMA) or homocysteine levelsto help confirm true deficiency, particularly in equivocal cases

More specifically, nanoemulsion of orlistat has been tried in order to overcome its high lipophilicity, to improve its dissolution and to avoid the pancreatic lipase inhibition caused by this pharmaceutical agent in vivo (258)