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This increased ATP consumption in astrocytes leads to greater glucose uptake, mediated by an increase in glucose transporter production, which in turn boosts glycolysis and lactate production via LDHA

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The inclusion and exclusion criteria were defined in direct accordance with the PICOS framework

In the traumatic brain injury model, SDC-1 in rat cerebral tissue decreased while increased in serum

Variability between genetically distinct populations Certain cell surface proteins exhibit a genetically determined high degree of inter-donor variability in expression, including CR1 and complement molecules C4A and C4B 31,32