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Principal component analysis showed that the cluster of all three repeats in the M group almost completely separates from the CTR group, the cluster of VM group has the largest overlap with CTR group, and the cluster of PM group has some overlap with both M and CTR groups (Supplementary Fig

10.1016/B978-0-12-385120-8.00015-2 Methods Enzymol

In the absence of validated protein, metabolite or genetic markers in CSF or blood, identifying patients most likely to benefit from ferroptosis-targeting therapies, assessing the treatment response or dose adjustment are difficult (9)

Based on the computational results, the five predicted non-toxic molecules were selected for the in vitro assay

Available from: Schuster S, Rubil S, Endres M, Princen HMG, Boeckel J-N, Winter K, et al

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