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After eight weeks of twice-daily use, the GHK-Cu version reduced wrinkle volume by about 56% and wrinkle depth by around 33% compared with the same cream without the peptide. Those are the kind of numbers that made people start taking copper peptides seriously in the first place

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Acta 1830 , 40734090 (2013)

doi: 10.1016/j.exphem.2015.11.002 103 IchinoseKUshigusaTNishinoANakashimaYSuzukiTHoraiYet al

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Zhong et al., 2009