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This effect is attributed to its capacity to restrain the differentiation of CD4+ T cells producing IFN- and IL-17A, alongside reducing the synthesis of correlated cytokines like TNF-, IL-6, IL-17A, and IFN- in splenic cells

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In addition, the Glu74 and Glu83 residues of ChaC2 are key for directing the conformation of the enzyme and regulating enzyme activity (20)

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Logistic regression models were used to analyse the longitudinal associations