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While glutathione is generally safe, some individuals may experience mild side effects

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Consequently, weights frequently rose under varying GSH, especially at 0.2 g L 1

A lack of response by the treated animal, or the development of new signs, may suggest that an overgrowth of nonsusceptible organisms has occurred

Still, some patients may not respond well to the positive effects of glucocorticoids including those who smoke, have certain type of asthma phenotypes, COPD or some interstitial diseases