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Roles of glutamine synthetase inhibition in epilepsy

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Some medications used to treat sleep disturbances include: clonidine, trazodone, melatonin, and antihistamines

The apparent K m values of AsGGT1 and AsGGT2 for -glutamyl- S -allyl-L-cysteine determined in this study (86 M and 1.1 mM, respectively) are lower than or comparable to those of partially purified onion GGT for -glutamyl- S -propenyl-L-cysteine ( K m = 1.68 mM) and for -glutamyl- S -methyl-L-cysteine ( K m = 0.55 mM