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These astrocytic cells undergo pathophysiological changes, propelling disease progression and altering synaptic transmission

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Expert Rev Neurother 17:227237 Valls A, Evers MM, Stam A, Sogorb-Gonzalez M, Brouwers C, Vendrell-Tornero C, Acar-Broekmans S, Paerels L, Klima J, Bohuslavova B, Pintauro R, Fodale V, Bresciani A, Liscak R, Urgosik D, Starek Z, Crha M, Blits B, Petry H, Ellederova Z, Motlik J, van Deventer S, Konstantinova P (2021) Widespread and sustained target engagement in Huntingtons disease minipigs upon intrastriatal microRNA-based gene therapy

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