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11 In the mitochondria, carrier proteins such as oxoglutarate carrier (also known as SLC25A11) and dicarboxylate carrier (SLC25A10) play roles in the mitochondrial transport of GSH, 79 and are therefore also regulatory targets of ferroptosis

The activity of -glutamylcysteine synthetase and that of GSH synthetase, two major enzymes involved in glutathione synthesis (Figure 1), remain unchanged in RBC with increasing density (Minnich et al., 1971) and get suppressed only in the cells showing the highest density on the Stractan gradient (Piccinini et al., 1995)

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