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Research has found morphological changes in ferroptosis cells, such as mitochondrial shrinkage and reduced mitochondrial cristae, in the intestinal epithelial cells of UC patients and experimental colitis mice

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Lipid peroxidation Lipid peroxidation refers to the process by which various types of free radicals, such as oxygen free radicals, peroxy free radicals, and hydroxyl free radicals, abstract electrons from lipids, producing reactive intermediates capable of further reactions, thereby initiating a lipid peroxidation chain reaction

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Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway