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Auto-oxidation is a chemical process where Glutathione converts to its oxidized form (GSSG) when exposed to oxygen or incompatible compounds

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Demographics, socioeconomic factors, metabolic data, associated liver disease, degree of severity of liver disease (Liver biopsy findings, FibroScan, CAP and stiffness) were compared between races and ethnicities through univariate and multivariate analysis

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A more likely interpretation could be that large, particulate immunocomplexes of aggregated HNE-SS-A2/Ro60 and autoantibodies stimulated the phagocytic and antigen-presenting activity of macrophages, which skewed the autoimmune response toward a prevailingly cytotoxic cell-mediated mechanism