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doi: 10.1016/j.psj.2022.102189 109 Al-KhalaifahHSIbrahimDKamelAEAl-NasserAAbdelwarithAARoushdyEMet al

This review aimed to explore the molecular mechanisms underlying APAP-induced liver injury, particularly inflammasome activation, and evaluate the current and emerging therapeutic strategies

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The early view that these channels are present only in non-excitable cells is not true

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Limitations of conventional therapies Modern pharmacological strategies for GI disorders rely on drugs such as antacids, proton pump inhibitors (PPIs), H 2 receptor antagonists, anti-inflammatory agents, antibiotics, and laxatives