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DonMDellAICalabreseFBenelliRMoriniMet al

The immunomodulatory effects of Se have been attributed primarily to the multiple activities of selenoproteins, particularly their role in maintaining redox balance (133, 134)

These findings underscore the complex and critical role of lactylation in myocardial IRI, acting as a double-edged sword with drastically different effects under various signaling pathways or intervention conditions