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Neuron 29 , 157169 (2001)

This 25% percent reduction in metabolism equates to an approximate deficit of 500600 cal per day

Proinflammatory cytokines such as IL-1, TNF-, and IL-6 can alter the expression of iron transporters and storage proteins, leading to increased cellular iron uptake and decreased iron export [214] through the upregulation of TfR1 and DMT1 expression and the downregulation of ferroportin expression [214,215]