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even large oral doses rarely exceed 220 mol/L in plasma (Padayatty et al., 2004), which could limit sustained systemic exposure at high altitude

Relevant roles of each specific IGFBPs will be further discussed when applicable to metabolism since there is a huge emerging world of IGFBPs independent actions

From a methodological standpoint, BPC-157 experiments often involve titration across multiple concentrations, time-course sampling, and pairing with imaging or molecular assays

(1992) IGF-1 and Especially IGF-1 Variants Are Anabolic in Dexamethasone-Treated Rats Biochem J 282:9197