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This foundational in vivo evidence has driven an expanding research programme using FOXO4-DRI as a molecular tool across multiple tissues and disease contexts

Among mice injected with a smaller number of tumor cells, the efficacy of the combination therapy was even greater, with a 65% increase in survival time [128]

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It remains unclear whether these outcomes are mediated directly or indirectly, but findings consistently show a measurable pain-modulating effect that varies with dosage

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Complexation with HP--CD yielded the best results in respect to drug release and the efficacy of the drug while maintaining its antimicrobial activity [34]