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It is composed of hydrophobic core (2-[N,N-(diisopropylamino) ethyl] methacrylate (DIPMA) and di(ethylene glycol) methyl ether methacrylate (DEGMA) copolymer) and hydrophilic shell (poly (ethylene glycol) monomethyl ether methacrylate (PEGMA) and 2-[N,N-(dimethylamino) ethyl methacrylate (DMAEMA) copolymer) encapsulated with the NK1R antagonist aprepitant (AP)

The peptides relatively short half-life in the bloodstream does not affect its stability in storage, but certain conditions can degrade it quickly

The lack of HrpA/HrpB TPS in the gonococcus would explain why the gonococcus remains predominantly confined within a vacuole during cellular infection, unlike the meningococcus, which is able to escape, and why the meningococcus, after reaching the cytosol, induces pyroptotic pathways during cellular infection, a phenomenon not described for the gonococcus