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Hepatocyte-Derived L-Carnitine restricts hepatitis B surface antigen loss through an immunosuppressive effect on germinal CenterRelated immune cells

These effects include energy metabolism, mitochondrial homeostasis, epigenetic regulation, endocrine regulation, inflammation and immune homeostasis, signal transduction, and neuromodulation (Fig

The role of L-carnitine is like that of the re-fueling team in the pit crew

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Abbreviations LC: L-carnitine TC: Total carnitine TMAO: Trimethylamine-N-oxide CHO: Carbohydrates IGF-1: Insulin-like growth factor-1 PI3K: Phosphoinositide-3-kinase Akt: Protein kinase B mTOR: Mammalian target of rapamycin S6K: S6 kinase 4E-BP: 4E-binding protein FoxO: Forkhead box O MuRF-1: Muscle-specific RING finger-1 atrogin-1: Muscle atrophy F-box mRNA: Messenger RNA BMI: Body mass index ROS: Reactive oxygen species References Bremer J