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1993;12:62-63 Rooyackers OE

POLG mutations in Alpers syndrome

(2022) 46:e14476

When similar clinical studies are performed in humans, we will all have some baseline level of nutrients in our bodies simply because of the food we eat

Selenium status, for instance, differs dramatically by geography: populations in low-selenium regions may benefit from targeted intake, whereas those in replete environments risk toxicity with supplementation (199)