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In the present study, the significant reductions of liver and plasma GSH (Table 3) and cystathionine concentrations (Table 2), in addition to the significant correlation between these two compounds, suggested that modulation of the methyl balance and the consequent reduction of Hcy can down-regulate the trans-sulfuration pathway in a dose-dependent response

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Nevertheless, whether dietary LC can depress lipid synthesis through regulating ER stress requires careful evaluation in further studies

[29] Several small studies didnt show decreased thyroid antibodies after selenium supplementation