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Interestingly, with progressive increase in IOP, autophagy is initially activated in the dendrites of RGCs and protects cells, but its subsequent activation in the cytoplasm disrupts homeostasis and induces cell death 21,22,70,71,72

These findings demonstrated that the Si-based agent suppressed LPO production through its antioxidant ability

Monobromobimane reacts with thiols, sulfide, thiosulfate, and sulfite to generate a fluorescent product with excitation/emission maxima at 394/490 nm

As ion channels are important therapeutic targets and many ion-channel drugs have already been approved for clinical trials, ORF3a is another good antiviral drug target 144

Liposomal delivery acts as a protective vehicle, bypassing the "digestion barrier" that destroys standard glutathione

The present study fills the missing mechanistic gap by identifying FABP5 as an upstream driver of this process