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This crosstalk between ferroptosis and immune cells exacerbates inflammation, leading to alveolar destruction and airflow limitation

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doi: 10.1097/MD.0000000000037682, 82

Following this sensor is a stretch of HEAT repeats that also bind the substrate (Figs

However, defective CFTR leads to dehydrated and thickened mucus, a hallmark of CF (162)

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