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A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Interestingly, the formation of TLS was significantly inhibited in the kidneys of sulfasalazine-treated mice (Figure 4, BD)

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If this insult persists, damaged airway epithelial cells release DAMPs such as HMGB1, mitochondrial DNA, ATP, and S100 proteins, which engage pattern recognition receptors (TLRs, NLRs) on resident and infiltrating immune cells and prolong signalling beyond the initial insult [20, 34]