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Description

As a possibility, changes in membrane PEBP1-dependent lipid signals determine the dual function of autophagy in ferroptosis

Hinman, M

2013;8(8):e70991

Choi J, Jang H, Choi J, Choi Y, Yang Y, Shim MK, et al

This Nrf2 activation may work in concert with the SAHH-dependent maintenance of the transsulfuration pathway, creating a multi-layered defense system wherein DJ-1 coordinately enhances both the synthesis (via transsulfuration) and the utilization (via Nrf2-target genes like GCLM) of glutathione