glutathione and napqi 5️⃣ Antidote: NAC (N-acetylcysteine) NAC
5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. The metabolic pathways of acetaminophen (APAP) in the human body. The Download Scientific Diagram Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram Solved The following figure shows the metabolism of the Acetaminophen metabolism. NAPQI, N acetyl p benzoquinone imine; CYP450, Download Scientific Diagram A crossomics analysis of acetaminopheninduced hepatotoxicity in rat liver Sumida 2015 Rapid Communications in Mass Spectrometry Wiley Online Library
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