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To examine the potential role of Erk1/2 as an MR-dependent stress signal linked to the ISR in HepG2 cells, we tested whether MR affected Erk1/2 activity and whether inhibition of Erk1/2 impaired MR-dependent induction of ISR genes

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Therefore, it is crucial to systematically collect data on inflammatory markers, such as cytokines and chemokines, alongside clinical assessments of semen parameters and erectile function

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