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This study also confirmed the limited activity of cationic amphipathic peptides in the presence of blood components, particularly for LL-37 and VFR12, where the range of values exceeded 64 g/mL

Nanocarrier-based mitochondrial delivery systems enable targeted administration of antioxidants or signaling modulators directly to infected tissues, improving pharmacokinetics and minimizing off-target toxicity (Wei et al., 2021)