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Although CCL2 plays an important role in inflammatory processes and can have a protective effect in various diseases, excessive levels can cause or worsen inflammatory conditions

[3] [10] Tretinoin When applied topically, tretinoin may cause itching, skin irritation, redness, or skin pain

doi 10.1016/j.phymed.2025.156602

We now know that klotho is a circulating hormone that can be found in body fluids, including blood and cerebrospinal fluid (95), and also in many territories where klotho is not expressed

Examination of innate immune cell pathways and their influences on allergic inflammation and B-cell phenotype may be another possible avenue to consider