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Injectable will provide a more potent and guaranteed systemic dose

10.1016/j.neuron.2013.07.033 212 LiuH.ColavittiR.RoviraI

While early-stage localized melanoma is often curable through surgical resection (Tyrell et al., 2017), the prognosis for metastatic melanoma remains poor, with distant metastatic cases exhibiting a 5-year survival rate of less than one-third (Tao et al., 2025), underscoring the complexity of clinical management