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249,250 In vivo studies confirm mitochondrial dysfunction in high-fat diet mice, which develop neuropathy marked by reduced nerve conduction velocities and decreased IENFD

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During this period, cortical GABAergic synapses are still undergoing the excitatory-to-inhibitory switch, which occurs mainly between P7 and P14 [10, 45,46,47, 49]

In addition, a metabolomics approach identified higher concentrations of long-chain acylcarnitines in incident dialysis patients, and these high concentrations were a marker of cardiovascular mortality after multivariable adjustment [15]

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