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Although the NO 3 pathway constitutes only a small portion of overall organic oxidation relative to OH, this pathway can still account for up to about 50% of the regional RONO 2 burden

However, the use of sulfonylureas or insulin in combination with metformin and pioglitazone may worsen DNP (75,76,97)

Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation

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