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Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition

PMCID: PMC10255885

[243] [245] CYP2D6, dopamine -hydroxylase (DBH), flavin-containing monooxygenase 3 (FMO3), butyrate-CoA ligase (XM-ligase), and glycine N -acyltransferase (GLYAT) are the enzymes known to metabolize amphetamine or its metabolites in humans

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[27], [36] Human RPLPO (large ribosomal protein) and PGK1 (phosphoglycerate kinase 1) were run as endogenous controls

Behavioral assessments were conducted in the open-field test, while molecular analyses were performed on medial prefrontal cortex tissue