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Effect of coenzyme Q(10) and alpha-tocopherol content of mitochondria on the production of superoxide anion radicals

Abstract In recent decades, scholarly investigations have predominantly centered on nanomaterials possessing enzyme-like characteristics, commonly referred to as nanozymes

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During pathological conditions, cytokines can also stimulate inducible nitrogen oxide synthase (iNOS) which results in the production of NO in astrocytes and microglial cells (Murphy, 2000), which can then combine with superoxide radicals to form the aforementioned peroxynitrite, facilitating excitotoxicity (Leist et al., 1997) and DNA damage, ultimately leading to cell death (Xia et al., 1996)