lipa c gene. Location of variants found in the patients analyzed Carrie Meek Gallagher - LIPA

Cell 176 , 4355.e13 (2019)

Kupffer cells along with liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs), and local immune cells, specifically unconventional T cells, natural killer (NK) cells, and hepatic dendritic cells make up the nonparenchymal liver cells, which are significant chemokine sources and responders

Accordingly, monitoring of total concentrations may be misleading since free concentrations may be substantially elevated in patients with hepatic disease whereas total concentrations may appear to be normal [see Boxed Warning, Contraindications (4), and Warnings and Precautions (5.1)]

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[48] Amphetamine is also the parent compound of its own structural class, which includes a number of psychoactive derivatives