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Participants completed survey instruments to measure HRQOL (PROMIS Profile-29), the Hospital Anxiety and Depression Scale (HADS), the Brief Health Literacy Screen (BHLS), and active post-traumatic stress (PTSD) symptoms using the Impact of Event Scale-Revised (IES-R)

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In this trial, treatment with cagrilintide resulted in significant weight loss compared to placebo, with greater reductions observed at all used cagrilintide doses (0.34.5 mg

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