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Bauer JA, Lupica JA, Schmidt H, Morrison BH, Haney RM, et al

Figure 4 3.2.3 Ferroptosis-mediated renal interstitial fibrosis Renal interstitial fibrosisan endpoint of CKDis promoted by ferroptosis in AKI models ( Regarding the integrated pathogenic network linking ferroptosis with inflammation, hypoxia, and fibrosis, in this network, the initial AKI-induced tubular injury (e.g., from I/R or nephrotoxicity) directly triggers ferroptosis via mitochondrial dysfunction and iron overload

Aspergillosis is a devastating disease for immunocompromised individuals (e.g., organ transplant recipients, those with AIDS, cancer, receiving bone marrow transplant, patients undergoing chemotherapy) caused by gliotoxin frequently resulted in renal failure with mortality rate of ~90% [349-351,357-360]

Synopsis Female fertility is impaired by chemotherapy in cancer patients

Journal of Medical Case Reports 13 (1): 336