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10.1016/j.biopha.2015.10.026 52 GanaiA

[5] When B12 and folate deficiency coexist, B12 replacement should be started before or alongside folic acid (typically 5mg daily) to avoid worsening neurological symptoms

Agarwal, U.K

for example, inhibiting the COX-2 pathway can change IEC cell activity, promote the apoptosis of IEC, and affect the subsequent pathogenic ability of the parasite