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N.LuoM.GuoA.-Z.YangS.-S.et al

(3) Genes with zero raw counts in 10% or more of samples were removed to further reduce noise

1 and Supplementary Tables 1 and 2)

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HIV-1 latency reversal by dCas9-VPR delivered by CD3 retargeted adenovirus vector Based on our previous findings, we selected one of the most effective HIV-1 specific gRNAs, gRNA-V, in combination with dCas9-VPR and the CD3-retargeted Ad vector to demonstrate efficient delivery of CRISPRa into target cells as well as effective HIV-1 provirus activation (Fig