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An Overview of Antiviral Peptides and Rational Biodesign Considerations

Functional studies have identified many key genes that mediate breast cancer organ-specific metastasis, and the expression of these genes in the primary tumor is likely to forecast the patients organ-specific metastasis (100, 101)

Although approved by the FDA within the recent decade, they are associated with a significant economic burden, often requiring multiple applications due to insufficient delivery (140, 141)

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In addition, although the SREBP-1cbinding sequences in these promoters share some common bases, the exact sequences vary hugely (49), which may also contribute to different binding affinity and different regulatory pattern