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Indeed, by targeting these unique features in these cancer cells, we recently showed that high dose vitamin C could selectively kill KRAS or BRAF mutant CRC cells

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Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia

This innovative strategy leverages cell membrane-derived surface properties to confer immune-evasive capabilities, prolong bloodstream retention, and enable tissue-specific cellular internalization, thereby addressing critical limitations in conventional nanodrug delivery systems [204,205,206,207,208]

452,453 In neurodegenerative diseases, neurotoxic substances from neuronal damage help to activate Drp1-mediated mitochondrial fission in microglia, down-regulate OXPHOS and ATP production with elevated ROS production, meanwhile motivating inflammasome formation

PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells