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Activation of these proteins induces a variety of responses, including cell proliferation, differentiation, and apoptosis in the epidermis [37,38]

10.1016/j.expneurol.2012.08.023 Summary Keywords neuropathic pain, oxidative stress, inflammation, mitochondrial dysfunction, TRP channels, antioxidants Citation Carrasco C, Nazirolu M, Rodrguez AB and Pariente JA (2018) Neuropathic Pain: Delving into the Oxidative Origin and the Possible Implication of Transient Receptor Potential Channels

It naturally occurs in high concentrations in skeletal muscle tissue, and therefore may support muscle vitality

Maxwell PH, Dachs GU, Gleadle JM, Nicholls LG, Harris AL, Stratford IJ, et al

Notably, it can induce oxidative stress in endothelial cells, initiating inflammatory responses (42)

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