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& Ebong, E

Notable examples of successful retargeting include sildenafil (initially developed to treat angina pectoris before being repurposed as an erectile dysfunction drug) and zidovudine (originally a chemical drug before becoming the first FDA-approved anti-HIV medication)

Renal tubulespecific knockout of Rest alleviates AKI through upregulating GCLM expression to inhibit ferroptosis

This condition involves multiple disruptions in cardiac energy metabolism, including substrate utilization, mitochondrial function, and ATP synthesis

Progressive multiple sclerosis: pathology and pathogenesis

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Desai B.S., Monahan A.J., Carvey P.M., Hendey B