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Tumor necrosis factor-alpha inhibitor for successful treatment of toxic epidermal necrolysis with severe infection: a case series

[DOI] [PubMed] [Google Scholar] 95.Riddell A., Babiker Z.O.E

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Excitotoxicity results from increased ROS production, which can lead to DNA damage, destabilization of proteostasis, and damage to organelles, ultimately leading to cell death

NAC treatment, however, caused only moderate recovery of aspirin-induced apoptosis in HepG2 cells suggesting additional factor(s), other than altered GSH pool, which could play a role in inducing apoptosis by ASA