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Considering that ALA could effectively stabilize hepatic Fe 2+ expression (Figure 1), and depress both levels of ferroptotic (Figure 2) and pro-apoptotic signaling (Figure 6), dietary supplementation with ALA may thus serve as a useful and practical way to prevent, or further counteract the CSD-induced liver injury and metabolic deficiency

The direct comparison upon using the same concentration of ruthenium of the molecular agent Ru(II)-OH and NP4 showed a significantly higher tumor accumulation of the nanoparticle formulation NP4 (Supplementary Fig

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Eur J Pharm Sci 42:7380 Xin W, Zhang L, Sun F, Jiang N, Fan H, Wang T, Li Z, He J, Fu F (2011b) Escin exerts synergistic anti-inflammatory effects with low doses of glucocorticoids in vivo and in vitro