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And, pretreatment with Moringa oleifera leaf extract (400 mg/kg/day for 14 days) produced anxiolytic effects in both FST and tail suspension test (TST) in the hepatic encephalopathy mouse model (139)

The exact mechanism of ferroptosis induction and its interaction with cancer cells is also not fully understood, and further studies are needed to elucidate how this pathway can be efficiently manipulated ( To translate these findings into clinical practice, further investigation is needed to elucidate the molecular mechanisms of ferroptosis, explore potential combinatory therapies, and develop robust biomarkers

An in vitro study (67), where human ectopic endometriotic cells were cultured with curcumin, showed a significant inhibition of TNF--induced secretion of IL-6, IL-8 and MCP-1 , known actors in the development of endometriosis

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Several autophagic genes (e.g., ATG4, ATG5) are expressed in the mouse cochlea from the embryonic phage until the adult phage ( ATG4 -null mice show the common pathological features of the inner ear (Mario et al., 2010)

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