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Tests confirmed excessive bacterial endotoxin levels in the compounded powder up to five times safe limit

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Existing evidence demonstrate that the leukemic blasts and LSCs have significantly higher levels of OXPHOS compared to HSCs and OXPHOS inhibition by Venetoclax is effective in targeting AML cells ( This study provided proof of principle concept that Venetoclax+ HMA mediated LSC specific amino acid, OXPHOS and antioxidant pathways activation inhibition can serve as curative therapy

Providing supplemental glycine theoretically supports this adaptation

Front Med (Lausanne) 2023;9:962337.ArticlePubMedPMC 25

J., Bakos, H