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References to Wegovy, Ozempic, Rybelsus, Mounjaro, or Saxenda, or other GLP-1 brands, are informational only

Exploratory analyses revealed links between ghrelin and eating-related depressive symptoms, and that higher BMI was more strongly associated with depressive symptoms in females than males

"The discovery and development of liraglutide and semaglutide." Frontiers in Endocrinology , 10, 155

Broader analysis across multiple clinical trials suggests that approximately 10% of patients across all indications and doses may discontinue semaglutide due to GI complaints, which is comparable to or slightly higher than other GLP-1 receptor agonists

Novo Nordisk has been investigating CagriSema through the REDEFINE programme, a series of Phase 3 clinical trials in adults with overweight or obesity

Allopurinol protects human glomerular endothelial cells from high glucose-induced reactive oxygen species generation, p53 overexpression and endothelial dysfunction