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In mouse models of autoimmune nephritis and diabetic nephropathy, Nrf2 deficiency ameliorates the disease phenotype (Table 1) [71,72]

Manic G, Obrist F, Kroemer G, Vitale I, Galluzzi L

In addition, suppression of apoplastic H 2 O 2 production through SlRBOH1 silencing inhibited the induction of GSNOR activity, leading to SNO accumulation at high temperature (Figure 6)