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Like most B vitamins, vitamin B6 is abundant in meat, fish, and poultry [57], and its deficiency leads to HHcy, which correlates with increased mortality from any cause [57]

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The RALS profile and negative-stain images showed that glutamine addition alone was sufficient to drive constitutively active forms of human GAC (K320A) and GLS2 (K253A) to form filaments, as the activation loop substitution effectively substitutes for the need of an anionic activator (Figs