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Power and sample size calculations for Mendelian randomization studies using one genetic instrument

Figure 5 illustrates the mechanisms by which the drugs act on their targets, primarily for the treatment of diabetes, DKD, and diabetes-related cardiovascular disease

Additional research has also demonstrated that professional carnitine administration can be used to lower clinically high blood pressure levels, treat congestive heart failure, manage cardiac ischemia (the restriction of blood flow to the heart), and peripheral arterial diseases, a condition characterized primarily by poor circulation in the legs (known as intermittent claudication)

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doi: 10.1038/s41419-018-0313-7

Targeting citrullination in autoimmunity: insights learned from preclinical mouse models